This paper presents the first co-designed 64-channel broadband PMUT (piezoelectric micromachined ultrasonic transducer) array integrated with a multi-level CMOS transmitter (TxCMOS) for wearable human artery ultrasound imaging. The system achieves a 70% bandwidth at 5 MHz and is driven by ±5V voltage, offering high performance and low power consumption suitable for non-invasive cardiovascular monitoring.
Key Contributions:
Broadband PMUT Array and Multi-Level CMOS Transmitter:
The 64-channel PMUT array is designed with multi-size PMUT elements to enhance the frequency response, achieving a 70% bandwidth. The multi-level CMOS transmitter enables precise control of the drive voltage and pulse shaping, which is essential for the high transmit and receive efficiency required for wearable applications.
The system features an 8.4 kPa/V/mm² transmit efficiency and 1.2 mV/V self-reception sensitivity, achieved with a low-voltage drive (±5V).
Integration with CMOS Low-Noise Amplifier (LNA):
Integration of the LNA at the output of the PMUT array boosts the received signal to 60 mVpp, providing a 6x voltage gain, which enhances the signal-to-noise ratio (SNR) for accurate pulse echo measurements.
Human Artery Imaging:
The system was demonstrated for the first time in vivo to capture M-mode ultrasound imaging of the brachial artery, with a 5 mm diameter at 15 mm depth. This imaging achieved 19 µm resolution in simultaneous upper and lower arterial wall tracking, enabling cardiac-cycle-correlated blood pressure calculation.
The deep tissue imaging capability (15 mm depth) and high resolution (19 µm) are crucial for real-time monitoring of arterial dynamics and blood pressure variations during cardiac cycles.
Experimental Results:
The PMUT array with 4-level pulsing was characterized underwater, showing high efficiency with pulse-echo tests and confirming the system’s broadband capability.
The system was also evaluated for its pulse echo signal, achieving 70% bandwidth and 11 mVpp received signals at 6.5 mm depth.
With the LNA, the system achieved significantly improved received signals, demonstrating its suitability for wearable devices.
System Integration and Performance:
The TxCMOS-PMUT platform was compared to state-of-the-art systems, showcasing superior performance with a 15 mm depth capability, high resolution, and low power consumption for continuous physiological monitoring.
Conclusion:
The co-designed TxCMOS-PMUT system successfully integrates a high-bandwidth PMUT array with a multi-level CMOS transmitter for wearable, non-invasive cardiovascular monitoring. This system is capable of high-resolution deep-tissue imaging and accurate blood pressure monitoring, providing a scalable solution for future healthcare applications. Future developments will focus on full SoC integration and AI-accelerated imaging algorithms for continuous monitoring.
OMeda (Shanghai Omedasemi Co.,Ltd) was founded in 2021 by 3 doctors with more than 10 years of experience in nanpfabrication. It currently has 15 employees and has rich experience in nanofabrication (coating, lithography, etching, two-photon printing, bonding) and other processes. We support nanofabrication of 4/6/8-inch wafers.